How LIVMARLI May Help
Whether you’re considering—or already preparing for—treatment, this brochure can help you learn more about LIVMARLI and how it works.
Once you or your child are prescribed LIVMARLI, Mirum Access Plus (MAP) experts will help you navigate your insurance coverage and share financial support options that may help with out-of-pocket costs.
If you have commercial insurance and your insurance coverage for LIVMARLI is approved, the LIVMARLI Savings Program can offer:
Eligible patients may pay as little as $10 out of pocket per fill*
If you are uninsured or coverage is denied, the MAP team will determine your eligibility for the Mirum PAP. Mirum PAP allows you to:
Receive LIVMARLI at no cost to you for up to 1 calendar year*
*Subject to program terms and conditions.
Receive support for every step of your LIVMARLI treatment.
Learn How to EnrollDesigned for busy families on the go, MAP Mobile is a convenient text messaging service that makes communicating with MAP even easier. Enroll in MAP Mobile to:
Understanding Alagille syndrome and its treatment can be difficult. Speaking with your or your child's doctor can help make things easier.
When partnering with your doctor, conversation is key. It’s helpful to be open and honest so you can work as a team toward your treatment goals. Here are a few things to get the conversation started.
Print the Discussion Guide to bring to your next visit.
Get the Itch✓ app: An easy-to-use journal designed to help you and your doctor make sense of itch severity and more.
Get the Itch✓ app: An easy-to-use journal designed to help you and your doctor make sense of itch severity and more.
Use Itch✓ twice a day—once in the morning and once in the evening—to create a journal of symptoms and observations. Get started by personalizing your profile, creating your child’s record, and logging your first journal entry.
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ALGSA is a non-profit organization with a goal of supporting the Alagille syndrome community by mobilizing resources, facilitating connections, promoting unity, and advocating a cure to inspire, empower, and enrich the lives of people affected by Alagille syndrome.
Visit the ALGSAYellow Alert is the Children’s Liver Disease Foundation’s awareness campaign promoting the early identification of liver disease in infants and their referral.
Visit Yellow AlertCLASS is an all-volunteer group helping children affected with liver diseases by addressing the emotional, educational, and financial needs of families.
Visit CLASSNORD is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them. NORD is committed to the identification, treatment, and cure of rare disorders through programs of education, advocacy, research, and patient services.
Visit NORDLIVMARLI is a prescription medicine used to treat cholestatic pruritus (itch) in patients with Alagille syndrome 1 year of age and older. It is not known if LIVMARLI is safe and effective in children under 1 year of age or in adults 65 years and older.
What are the possible side effects
of LIVMARLI?
LIVMARLI can cause serious side effects, including:
Changes in liver tests. Changes in certain liver tests are common in patients with Alagille syndrome but may worsen during treatment with LIVMARLI. These changes may be a sign of liver injury and can be serious. Your health care provider should do blood tests before starting and during treatment to check your liver function. Tell your health care provider right away if you get any signs or symptoms of liver problems, including:
Stomach and intestinal (gastrointestinal) problems. LIVMARLI can cause stomach and intestinal problems, including diarrhea, stomach pain, and vomiting during treatment. Tell your health care provider right away if you have any of these symptoms more often or more severely than normal for you.
A condition called Fat-Soluble Vitamin (FSV) Deficiency caused by low levels of certain vitamins (vitamins A, D, E, and K) stored in body fat. FSV deficiency is common in patients with Alagille syndrome but may worsen during treatment. Your health care provider should do blood tests before starting and during treatment.
Other common side effects reported during treatment were bone fractures and gastrointestinal bleeding.
Tell your health care provider about all medicines that you take. LIVMARLI may affect the way some other medicines work, and some other medicines may affect the way LIVMARLI works. If you take a medicine that lowers cholesterol by binding bile acids, such as cholestyramine, colesevelam, or colestipol, take it at least 4 hours before or 4 hours after you take LIVMARLI.
LIVMARLI is taken by mouth, 1 time each day, 30 minutes before the first meal of the day. Be sure to use the provided oral dosing dispenser to accurately measure the dose of medicine.
These are not all of the possible side effects of LIVMARLI. Call your health care provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.