Easier Access for Everyone

Making Information Accessible for Patients and Their Families

Mirum is committed to accessibility in everything we do. We value the inclusion of everyone, with consideration of their needs and challenges, and work to ensure this is shown in the experiences we design and websites we create. With this in mind, we continually take steps to improve LIVMARLI.com and ensure it complies with best practices and standards.

Current Accessibility Features

Accessibility and universal usability are important parts of making informed health decisions. Rooted in our mission to transform the lives of patients and their families, the Mirum team utilizes technology, advocacy, and bold action to promote the best experiences for all audiences by employing:

  • Industry standard user-experience (UX) principles
  • Website designs with color contrast and accessibility at the forefront, according to Web Content Accessibility Guidelines (WCAG) 2
  • Inclusive design principles that celebrate the full scope of human diversity
  • Transcripts for our video content, ensuring they are accurate and complete

Our Website and Pages

Our website and landing pages are built with accessibility in mind, according to WCAG 2 best practices. The following issues are considered and remediated:

  • Title attributes for additional information when text is not available
  • Appropriate alternative text detail for images and other non-text elements
  • Graphics and interactive content
  • Form accessibility
  • Table accessibility
  • PDF and web-based brochure accessibility
  • Hierarchy
  • Line length
  • Font choice
  • Color contrast
  • Transcripts
  • Avoiding repetitive flashing in motion design

Investing in Accessibility

At Mirum, we believe it is our responsibility to ensure that content is accessible to everyone. We are dedicated to exploring new solutions, tools, and products to help enhance the overall experience. As we continue to improve our website, we will reflect those changes here within our accessibility statement and keep you informed of our efforts.

Learn More About Accessibility

The Americans with Disabilities Act (ADA)

Website accessibility standards under Title II of the ADA

Federal Communications Commission (FCC)

Twenty-First Century Communications and Video Accessibility Act

Web Accessibility Initiative (WAI)

International standards for the web to improve accessibility for people with disabilities

Web Content Accessibility Guidelines (WCAG) 2 Checklist

Compiled by Web Accessibility in Mind (Web AIM)

World Wide Web Consortium (W3C)

Strategies, standards, and resources to make the web accessible to people with disabilities

We Want to Hear From You

If you encounter any accessibility issues, please let us know. We’re here to help you get the information you need.

You can reach us by visiting the Mirum Pharmaceuticals Contact Page.

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LIVMARLI is a prescription medicine used to treat cholestatic pruritus (itch) in patients with Alagille syndrome 1 year of age and older. It is not known if LIVMARLI is safe and effective in children under 1 year of age or in adults 65 years and older.

Important Safety Information

What are the possible side effects 

LIVMARLI can cause serious side effects, including:

Changes in liver tests. Changes in certain liver tests are common in patients with Alagille syndrome but may worsen during treatment with LIVMARLI. These changes may be a sign of liver injury and can be serious. Your health care provider should do blood tests before starting and during treatment to check your liver function. Tell your health care provider right away if you get any signs or symptoms of liver problems, including:

  • nausea or vomiting
  • skin or the white part of the eye turns yellow
  • dark or brown urine
  • pain on the right side of the stomach (abdomen)
  • loss of appetite

Stomach and intestinal (gastrointestinal) problems. LIVMARLI can cause stomach and intestinal problems, including diarrhea, stomach pain, and vomiting during treatment. Tell your health care provider right away if you have any of these symptoms more often or more severely than normal for you.

A condition called Fat-Soluble Vitamin (FSV) Deficiency caused by low levels of certain vitamins (vitamins A, D, E, and K) stored in body fat. FSV deficiency is common in patients with Alagille syndrome but may worsen during treatment. Your health care provider should do blood tests before starting and during treatment.

Other common side effects reported during treatment were bone fractures and gastrointestinal bleeding.

Tell your health care provider about all medicines that you take. LIVMARLI may affect the way some other medicines work, and some other medicines may affect the way LIVMARLI works. If you take a medicine that lowers cholesterol by binding bile acids, such as cholestyramine, colesevelam, or colestipol, take it at least 4 hours before or 4 hours after you take LIVMARLI.

LIVMARLI is taken by mouth, 1 time each day, 30 minutes before the first meal of the day. Be sure to use the provided oral dosing dispenser to accurately measure the dose of medicine.

These are not all of the possible side effects of LIVMARLI. Call your health care provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Patient Information: English | Español